Support TDRA

We are accepting donations. Click here for details on how you can support us.

We would like to acknowledge and thank the Napier family and friends for their support of the TDRA. Donations were made in memory of Barry Napier, who passed away on March 13, 2017 after a long battle with dementia.

TDRA Cognitive Assessments

TDRA Celebration Event – Oct 18, 2017


Women with high physical fitness at middle age were nearly 90 percent less likely to develop dementia decades later, compared to women who were moderately fit, according to a new study. The study meas [...]

African Americans with a common genetic variation are at increased risk for developing Alzheimer's disease, while European Americans with the same variation are not, according to a new study. [...]

The largest genetic study of stroke to date triples the number of known genetic risk factors for the disease and also should enable researchers to find novel treatments for dementia. [...]

As we get older, it's not uncommon to experience 'senior moments,' in which we forget where we parked our car or call our children by the wrong names. And we may wonder: Are these memor [...]

Medical researchers have identified novel biomarkers of risk for future dementia. [...]

Treatments targeted to enhance brain neurotrophic factor signaling could improve memory functions in Alzheimer's disease even though they don't alter brain amyloid burden, according to recen [...]

'Epigenetic landscape' is protective in normal aging, impaired in Alzheimer's diseaseResearchers profiled the epigenomic landscape of Alzheimer's brains, specifically in one of the regions affected early in AD, the lateral temporal lobe. They compared these to both younger and el [...]

For the first time, scientists have determined that an Alzheimer's disease (AD) polygenic risk score can be used to correctly identify adults with mild cognitive impairment (MCI) who were only in [...]

Stem-cell study points to new approach to Alzheimer's diseaseImproving the trafficking of brain-cell proteins to reduce toxic buildup holds possibilities for new therapies against Alzheimer's disease. [...]

Brain injury may boost risk of Alzheimer's earlier in lifeConcussions and other traumatic brain injuries may increase the risk of developing Alzheimer's disease earlier in life, according to a new study. [...]

A new study shows that the closer a person gets to the age at which their parent exhibited the first signs of Alzheimer's, the more likely they are to have amyloid plaques, the cause of the cogni [...]

Patients may score slightly lower on certain memory tests after having surgery and anesthesia. [...]

Largest study of its kind finds alcohol use biggest risk factor for dementiaAlcohol use disorders are the most important preventable risk factors for the onset of all types of dementia, especially early-onset dementia. This according to a nationwide observational study of ove [...]

Protein levels in spinal fluid correlate to posture and gait difficulty in Parkinson'sLevels of a protein found in the brain called alpha-synuclein are significantly lower than normal in cerebrospinal fluid collected in Parkinson's disease patients suffering from postural instabil [...]

Data detectives shift suspicions in Alzheimer's from usual suspect to inside villainThe pursuit of the usual suspect in Alzheimer's research may be distracting from a more direct culprit in the disease, according to a study that analyzed data from 51 published experiments. P-tau [...]

Doctors who work with individuals at risk of developing dementia have long suspected that patients who do not realize they experience memory problems are at greater risk of seeing their condition wors [...]

Amyloid protein transmission through neurosurgeryAmyloid beta pathology -- protein deposits in the brain - might have been transmitted by contaminated neurosurgical instruments, suggests a new study. Researchers studied the medical records of four p [...]

Poor fitness linked to weaker brain fiber, higher dementia riskScientists have more evidence that exercise improves brain health and could be a lifesaving ingredient that prevents Alzheimer's disease. [...]

Alzheimer's disease reversed in mouse modelResearchers have found that gradually depleting an enzyme called BACE1 completely reverses the formation of amyloid plaques in the brains of mice with Alzheimer's disease, thereby improving the a [...]

New research has found that pimavanserin significantly improves psychosis symptoms in people with Alzheimer's disease, without the devastating side-effects of currently used antipsychotics. The r [...]

A new study suggests an association between overactive and cytosolic BRCA1, the major guardian of genomic stability, and neurons death in Alzheimer's disease (AD). Upregulated BRCA1 is associated [...]

After more than a decade of research, this much we know: it's good for your brain to know another language. A new study goes further, however, focusing specifically on the effects of knowing a se [...]

Study offers new insights into how brain and rest of body communicate. [...]

Half of all dementias start with damaged 'gatekeeper cells'Research sheds new light on how a breakdown in the brain's vascular system predates the accumulation of toxic plaques and tangles in the brain that bring about Alzheimer's disease. The resea [...]

Low levels of alcohol good for the brain, study showsWhile a couple of glasses of wine can help clear the mind after a busy day, new research shows that it may actually help clean the mind as well. The new study shows that low levels of alcohol consumpt [...]

Traumatic brain injuries increase the risk of a dementia diagnosis for more than 30 years after a trauma, though the risk of dementia decreases over time, according to a new study. [...]

Brain pacemaker study shows promise in slowing decline of Alzheimer'sResearchers have studied how using an implant -- likened to a pacemaker for the brain -- could help Alzheimer's patients to retain cognitive, behavioral and functional abilities longer while also [...]

People with Alzheimer’s disease have disturbances in their internal body clocks that affect the sleep/wake cycle and may increase risk of developing the disorder. Researchers have found that such circ [...]

A diet created by researchers may help substantially slow cognitive decline in stroke survivors, according to preliminary research. The finding are significant because stroke survivors are twice as li [...]

Enhanced lifestyle counselling prevents cognitive decline even in people who are carriers of the APOE4 gene, a common risk factor of Alzheimer's disease, according to a new study. [...]

Researchers report that solanezumab, a monoclonal antibody-based treatment for Alzheimer's disease developed by Eli Lilly that targets amyloid plaques, did not significantly slow cognitive declin [...]

Personality changes and behavior problems that come with Alzheimer's disease are as troubling as memory loss and other mental difficulties for caregivers and those living with the condition. Rese [...]

In a new study, researchers have examined the effects of the disease on the functioning of mitochondria -- structures performing a variety of essential tasks, including supplying cells with energy. [...]

Curcumin improves memory and moodDaily consumption of a certain form of curcumin -- the substance that gives Indian curry its bright color -- improved memory and mood in people with mild, age-related memory loss. [...]

Frequently encountered in the elderly, Alzheimer's is considered a neurodegenerative disease, which means that it is accompanied by a significant, progressive loss of neurons and their nerve endi [...]

A new, first-of-its-kind study was designed to assess whether cognitive training, a medication-free treatment, could improve MCI. Studies show that activities that stimulate your brain, such as cognit [...]

An increasing number of older adults are reporting cognitive impairment in their families over the past two decades, according to a new study. [...]

A new study suggests an association between elevated amyloid beta levels and the worsening of anxiety symptoms. The findings support the hypothesis that neuropsychiatric symptoms could represent the e [...]

One of the most intriguing properties of the brain is its means to undergo synaptic plasticity which represents the basis for learning and memory, abilities that severely decline in the case of a deme [...]

Recent advances in brain imaging have enabled scientists to show for the first time that a key protein which causes nerve cell death spreads throughout the brain in Alzheimer's disease -- and hen [...]

Researchers have identified several new genes responsible for Alzheimer's disease (AD) including those leading to functional and structural changes in the brain and elevated levels of AD proteins [...]

Diabetes drug 'significantly reverses memory loss' in mice with Alzheimer'sA drug developed for diabetes could be used to treat Alzheimer's after scientists found it 'significantly reversed memory loss' in mice through a triple method of action. This is the fi [...]

For patients with mild cognitive impairment, don't be surprised if your health care provider prescribes exercise rather than medication. A new guideline for medical practitioners says they should [...]

Inflammation drives progression of Alzheimer'sInflammatory mechanisms caused by the brain's immune system drive the progression of Alzheimer's disease, according to new research. These findings, which rely on a series of laboratory expe [...]

Dementia affects millions of people worldwide, robbing them of their ability to think, remember and live as they once did. In the search for new ways to fight cognitive decline, scientists report that [...]

Dementia with Lewy bodies has a unique genetic profile, distinct from those of Alzheimer's disease or Parkinson's disease, according to the first large-scale genetic study of this common typ [...]

Canola oil is one of the most widely consumed vegetable oils, yet little is known about its health effects. Now, a study links canola oil consumption in the diet with worsened memory, worsened learnin [...]

Population of Americans with Alzheimer's will more than double by 2060About 15 million Americans will have either Alzheimer's dementia or mild cognitive impairment by 2060, up from approximately 6.08 million this year. The findings highlight the need to develop pre [...]

Healthy mitochondria could stop Alzheimer'sUsing a bioinformatics and experimental approach, scientists have found that rendering mitochondria resistant to damage can halt diseases caused by amyloid toxicity, such as Alzheimer's disease. [...]

Alzheimer's damage in mice reduced with compound that targets APOE genePeople who carry the APOE4 genetic variant face a substantial risk for developing Alzheimer's disease. Now, researchers have identified a compound that targets the APOE protein in the brains of m [...]